diff --git a/requirements.txt b/requirements.txt
index e71bf8e81..1a7e462cc 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,5 +1,5 @@
 # -*- conf-mode -*-
-setuptools>=18.5,<45.0			# Require this first, to prevent later errors
+setuptools>=40.3.0,<45.0			# Require this first, to prevent later errors
 #
 argon2-cffi>=16.1.0		# For the Argon2 password hasher option
 beautifulsoup4>=4.5.0
@@ -50,16 +50,16 @@ pyang>=1.7.2
 pyflakes>=0.9.2
 pyopenssl>=17.5.0		# Used by urllib3.contrib, which is used by PyQuery but not marked as a dependency
 pyquery>=1.2.13,!=1.2.14	# Pyqyery 1.2.14 fails on some selectors or stacked selectors
-python-dateutil>=2.2
+python-dateutil>=2.4
 python-magic>=0.4.6
-python-memcached>=1.48		# for django.core.cache.backends.memcached
+python-memcached>=1.56		# for django.core.cache.backends.memcached
 python-mimeparse>=1.6		# from TastyPie
 pytz>=2014.7
 #pyzmail>=1.0.3
 requests!=2.12.*
 rfc2html>=2.0.1
 selenium>=2.42,<3.8.1
-six>=1.9.0
+six>=1.10.0
 sqlparse>=0.2.2
 svn>=1.0.1
 tblib>=1.3.0